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The method provided LODs that ranged from 0.6 to 3.5 μg·kg−1 [ 75].
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Under optimized conditions, the newly developed method provided high extraction recoveries (93.8 99.1%) and low LODs (ca. 0.3 μg L−1) for three phthalate metabolites in human urine.
Under optimized extraction conditions, the method provided satisfactory linearity in the range 1 500 ng mL−1, low LODs (0.3 0.7 ng mL−1), good repeatability and reproducibility (RSD% (n = 5) < 4.5) with the pre-concentration factors higher than 130-fold.
The limit of detection (LOD, S/ N = 3) for 14,15-DiHETrE 14,15-DiHETrEETrE wand0.14nmol L−15 -EpETrEon column) and method provided for both analytes a broad linear detection range over three orders of magnitude (R ≥ 0.999) from the limit of quantification (LOQ, S/ N = 9) up to 800 nmol L−1.
The proposed method provides relatively low limits of detection (LOD; 0.001 μg/mL).
This method provides a quantitative instruction for generating discrete LODs.
Figure 1(b) shows the LOD score values for the LD estimates from the three methods and demonstrates that the present method provides much more likely estimates of linkage disequilibria in the vicinity of the disease causing site than the other methods under comparison.
All of these methods provide similar results.
Additional methods are provided in Methods S1.
Detailed methods are provided in File S1.
Out of the 12 families, seven provided positive LOD scores for this region.
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