In addition to classical methodologies for studying G-quadruplex structures, such as circular dichroism, nuclear magnetic resonance or crystallography, the electrochemical methods present very high sensitivity and selectivity and have been used for the rapid detection of the conformational changes from single-strand to G-quadruplex.
Semi-Markov Chain approaches, which are based on process sojourn time considerations, combined with smart monitoring sensor systems and advanced nonlinear Finite Element simulation methods, present very promising approaches for the realistic description of concrete fatigue processes and their redistribution characteristics and in consequence for the prediction of the remaining lifetime.
Thus, the model and method developed present very good convergence behavior in computation and provide accurate predictions of the mechanical behaviors and displacement distributions in the nanotubes.
The SGC method presented is very useful and convenient to assess the hazardous risks of chemicals.
The method presented is very useful for decision-makers in order to evaluate the inclusion of new technologies to improve the chemical process operation and topological designs.
The methodology of X-FEM, different from that of the classical finite element method, presents a very particular interest since it does not force the discontinuities to be in conformity with the borders.
The results obtained by the method presented coincide very well with the results obtained by numerical integration for the Duffing van der Pol oscillator withf u,u =μ(1−u2)u−βu3.
It appears that the methods present a very variable efficiency, from those quite unable to detect, in our conditions, some HTs to that which are able to detect almost all (Figure 1).
The method presented here is very simple but shows very competitive performance compared with other methods in the challenge.
In this commentary, the methods are presented very briefly, and we encourage readers to use the references included for a deeper understanding.
