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Comorbidities – we applied the Elixhauser method, originally defined by Elixhauser et al. [ 38] and updated by Quan et al. [ 39].
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Unlike traditional DQ methods, which were originally defined on meshes of node points, the RBFDQ method requires no mesh-connectivity information and allows straightforward implementation in an unstructured nodes.
However, ADANET, GENIE3, CLR, C3NET, MRNET, and ARACNE methods, as they are originally defined, take a multifactorial matrix as an input, which is unavailable in this challenge.
The S-transform was originally defined as a method of determining the local spectrum of a time series, through the use of a translating, real Gaussian window that dilates to accomodate the different cycle durations of different frequencies.
Chemogenomics is originally defined as a method that discovers active and/or selective ligands for biologically related targets in a systematic manner [43] and an extremely broad and significant example of chemogenomics is reported by Keiser et al. who quantitatively grouped and related hundreds of drug targets based on the chemical similarity of 65.000 ligands [44].
Co-expression modules were originally defined by bi-clustering methods (see details in [40]).
They were originally defined as pharmacologically active, nitrogen-containing basic compounds of plant origin.
"I think it's every bit as rigorous as originally defined," Mr. Levy said.
As originally defined, the kilogram was represented in the late 18th century by a solid cylinder of platinum.
Two elements that originally defined performance art as a medium, unpredictability and ephemerality, were missing.
Together, these represent the originally defined suspension effect (ODSE).
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