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A robustness test of a solid-phase microextraction-based method optimised for the simultaneous determination of chloroanisoles and acetyl-chlorophenols implicated in the presence of corky taste in wine has been carried out using a hybrid experimental design.
"The second method optimised scores through gradient descent — a mathematical technique commonly used in machine learning for making small, incremental improvements — which resulted in highly accurate structures.
In targeted metabolomics a pre-defined subset of metabolites are chosen and a particular analytical method optimised for that subset is used [7].
Plasma levels of gemcitabine and its metabolite 2′, 2′-difluorodeoxyuridine (dFdU) were determined by a previously described reverse-phase high-performance liquid chromatography with ultraviolet detection (HPLC-UV) method optimised for the present study (Wang et al, 2003).
Based on information from a completely recorded genealogy, this method optimised the genetic contribution (i.e., number of offspring) of the available candidates to minimise coancestry between individuals of the current population and the foreign founders.
We have used a 200-mg Waters Sep-Pak tC18 reversed-phase cartridge with a method optimised for the recovery of oxysterols with a side-chain hydroxyl group (e.g. 22 R-, 24 S-, 25- and 26-HC) and for cholestenoic acids (e.g. 3β-hydroxycholest-5-enoic acid and 3β,7α-dihydroxycholest-5-enoic acid).
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In LR the weight vector is selected to maximising the (log) likelihood, whereas our method optimises Youden's J statistic (see Methods).
The method optimises surgical access during lung resection and oesophagectomy procedures.
Continued medication supply could be via repeat prescribing or other management services, whichever method optimises patient safety.
Radiolabelling of DATATOC was evaluated at ambient temperature using 68Ga PP by each of the four methods, optimised in terms of the labelling pH.
The goal-based adaptive methods optimise the angular discretisation to minimise the error in a specific functional of the solution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com