Seabrook, who has been a staff writer since 1993, became obsessed with his own family history after the birth of his son, in 1998, and began to investigate both traditional and high-tech methods of uncovering his forebears.
In this chapter, we will underscore how to design experiments in order to be able to answer questions posed by the investigator, the different normalization strategies used and their assumptions, the different types of statistical analysis and adjustments for multiple testing, methods of uncovering patterns in the data, and strategies to find meaning in the results.
In other words, the proposed method is capable of uncovering genes that are associated with diseases, whose genetic bases are completely unknown.
Joseph N. Straus's article in Musical Quarterly on the "myth" of "serial 'tyranny' " hails from the prayer book of the "numbers-don't-lie" sect of music scholarship, displaying a quaintly modern faith in empirical methods as capable of uncovering important truths about human activity ["Midcentury Serialists: The Bullies or the Besieged?" by Anthony Tommasini, July 9].
Depending on the theoretical assumptions and metrics included, these methods are capable of uncovering substructures that represent specific biological functions.
Though a few such genes have come to light through guesswork, genomewide scans are the most promising method for uncovering the roots of multigenic disease.
Phenomenology is a philosophical method for uncovering the structure of lived experience by describing what it is like from a first person perspective.
Qualitative interviews are a useful method for uncovering the meanings and understandings of the informants.
In this paper we have analysed gene expression data with a variety of computational methods with the aim of uncovering transcription factors that potentially dysregulate in MS or one or more of its disease subtypes.
Archaeoastronomy uses a variety of methods to uncover evidence of past practices including archaeology, anthropology, astronomy, statistics and probability, and history.
