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Up until now, early case detection and treatment of cases is the only and most effective method of TB control [ 6].
This study indicated there are several challenges associated with facility based daily DOT as a method of TB treatment supervision in public health facilities in Addis Ababa.
This study highlighted the several challenges and difficulties surrounding a facility based DOT as a method of TB treatment supervision in public health facilities in Addis Ababa.
In most high burden settings, less emphasis is placed on screening and treatment of LTBI in general populations and preventive therapy remains underutilized in the HIV-infected population as a method of TB control [ 36, 37].
This logic underlies the WHO's recommendation of directly observed therapy as the international method of TB control and is supported by data reflecting decreased relapse and resistance rates as a result of its implementation [ 17].
Our aim, therefore, is to examine the utility of a molecular method of TB detection within an incarcerated population to find a more rapid alternative that enhances the active search for respiratory symptoms.
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Traditional methods of TB detection and anti tB drug susceptibility assays are time consuming and with a steep rise in number of MDR tB cases the need of the hour is rapid diagnostic methods like direct drug susceptibility testing in liquid medium, molecular hybridization methods and RealTime PCR.
Acceptable methods of TB screening include the purified protein derivative skin test and QuantiFERON Gold test (where available).
In these cases a mixed infection with an already resistant strain may have been obscured by the conventional methods of TB culture and DST.
The other conventional diagnostic methods of TB, such as chest radiographs, urine, and sputum cultures are not specific for FGTB, but are helpful to rule out dissemination to other organs.
Now a group in the Republic of Korea reports what they believe could be a potent new method of fighting TB: a combination of cheap drugs and a DNA vaccine.
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