The methods of subject recruitment, sample collection, and C. albicans isolation and identification were described in our previously published study [ 4].
Methods of subject recruitment as well as timing and manner of urine collection and processing were comparable between the CARD and ARI cohorts, and preliminary analyses of mean urinary porphyrin and Hg levels by subject source indicated no significant differences within age groupings.
Details of subject recruitment methods, data collection and laboratory testing for the WAS have been reported elsewhere [6].
These recommendations include among others, the following items: indicating time period and location of subject recruitment, success rate for DNA acquisition, sample tracking methods, and genotyping with a second technology in a second laboratory.
Figure 1 shows the flow of subject recruitment.
BA assisted in the development of the study protocol, methods for subject recruitment, and statistical analyses.
A detailed description of the design and methods for subject recruitment, scheduled returns, epidemiologic data, medical procedures, and biological sampling has been described elsewhere [ 12].
Detailed description of the study area and population, including the methods of subject randomisation, recruitment and follow-up were given elsewhere [ 14]; only the methods used in the pneumococcal carriage component will be briefly discussed here.
The Health Services Research and Development Service (HSR&D) of the Veterans Administration has had no role in the design, methods, subject recruitment, data collections, analysis, and preparation of this paper.
The Archstone Foundation and the U.S. Department of Veterans Affairs (VA) Greater Los Angeles Healthcare System had no role in the design, methods, subject recruitment, data collections, analysis and preparation of this paper.
