However, the authors discussed that their method of propagation of lineages (transferring the fastest-growing hyphal tips) might not be the best approach to allow efficient competition and adaptive response [ 13].
A variety of methods for lineage analysis, generally termed clonal assays (reviewed in [5]), rely on marking some cells and tracing their progeny.
Specifically, we wanted to determine whether biologically interesting patterns can be detected using this method in terms of lineage- or clade-specific differences in turnover parameters.
The remainder of this article presents the LineageProgram model (Section 2), a comparative analysis of LineageProgram with other methods on lineage-associated expression data from motor neuron and pancreatic development (Section 3) and a conclusion about what we have learned about using lineage information (Section 4).
Gould never embraced cladistics as a method of investigating evolutionary lineages and process, possibly because he was concerned that such investigations would lead to neglect of the details in historical biology, which he considered all-important.
Both the phylogenetic and counting methods of identifying lineage-specific duplications yield similar results; therefore, our findings are not an artifact of the method used to identify duplicated genes.
Palmiter et al. developed a method of deleting specific cell lineages that entailed microinjection into fertilized eggs of a chimeric gene in which a cellspecific enhancer/promoter is used to drive the expression of a toxic gene product [ 106].
The Methods section "Extinction of Lineages... .......... bristles with graphical language ("below", "above", "proximal", "distal" etc)., but all these complicated descriptions are not easy to picture.
Population assignment analyses based on these parameters may serve as useful methods for delimiting the early stages of lineage divergence [18], [38].
We developed the method of CLoNe to enable clonal lineage analysis of the progeny of specifically targeted progenitor cells.
