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With the aim of developing a novel diagnostic method of leukemia, we report in this paper the use of DL to spectrally discriminate between normal and leukemic human sera.
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In addition to being one of the first to report on the cancer-inducing effects of radiation exposure, he studied its effects on bone marrow cells and developed a method of treating leukemia.
Our findings indicate that SPDT could be an effective method for the treatment of leukemia, and that antitumor immunity may play a key role in this process.
Results in this work contribute to the development of a novel optical method for the early diagnosis of leukemia.
This high rate was within the range reported in independent studies for various clinical populations (0.5 15%) and highlighted the complementary role of molecular and cytogenetic methods in the clinical management of leukemia.
The method is showing early promise in treating certain kinds of leukemia and other blood cancers.
We evaluated the efficacy of an SPDT method for treating leukemia using a Brown Norway myeloid leukemia (BNML) rat model with the LT12 cells engineered to express GFP.
We next investigated the consistency of gene expression measurements of leukemia samples when using different total RNA extraction methods by performing an unsupervised hierarchical clustering analysis.
A comparison of the proposed method with the t-test on the expression profiling of the bone marrow of Leukemia patients was conducted.
This provides an effective method to reproduce precise reciprocal tumor-associated chromosomal translocations to better understand the initiation of leukemia and sarcoma.
To investigate the antitumor effects of selenite in vivo, xenograft models of leukemia NB4 cells were established as described in the Materials and Methods.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com