Sentence examples for method of escalation from inspiring English sources
Dose selection was carried out utilising the flexible Bayesian method of Escalation with Overdose Control (EWOC) (Tighiouart and Rogatko 2010), a fully adaptive, real time dose-finding method that uses individual patient experiences to select subsequent doses, allowing for more rapid dose escalation while minimising the number of patients who are underdosed.
Trials using the continual reassessment method of dose escalation are simulated, with a modification of the rules to allow patients to choose a higher dose if they wish.
The ratio is similar to that of other platinum species and suggests that the method of dose escalation used in this study was appropriate for AMD473.
Two-dimensional high-dose-rate brachytherapy (2D-HDR-BT) is an effective method of dose escalation for local tumor control in early T-stage nasopharyngeal carcinoma (NPC).
The modified-Fibonacci-sequence was the most common method of dose-escalation (92/197, 46%).
This method of communication and escalation of care became largely redundant with the dedicated ward-based clinical team on the new hospital site.
Results were consistent across five different methods of estimating dose escalation, with etanercept having lower dose escalation rates than adalimumab.
Patients receiving etanercept had a significantly lower rate of dose escalation (range 0.4 2.9%) than those receiving adalimumab (range 7.0 28.3%) according to all five methods of calculating dose escalation for both new and continuing patients (P < 0.001) (Table 3).
In this study, five different methods of calculating dose escalation were used; most of these methods have been used in previously published studies [ 11– 17, 17, 20, 21].
The most widely used method of increasing dose intensity has been dose escalation.
