Sentence examples for method of allele from inspiring English sources

Therefore, to reduce any overestimation of rare alleles, we used a round-robin method of allele frequency estimation [ 51].

Allele-specific hybridization (ASH) is a method of allele discrimination in genotyping.

We use the quantitative polymerase chain reaction (qPCR) as our method of allele quantification, but any method that can reliably distinguish the difference between one and two copies of the target gene can be used to develop an LOA assay.

3 This method of allele targeting, although quick, bears several risks.

Allele detection was carried out using the MALDI-TOF mass spectrometry method of allele determination on a Sequenom platform.

There was a small change in α as a result of the round-robin method of allele frequency estimation (Additional file 2: Table S2).

Approximately 5.5% of the genotypes were created with an in-house developed method of allele-specific primer extension on microarrays, as previously described [36].

We compared the UV classification methods of allele frequency, Polyphen, sequence conservation, and the GMS by examining the pairwise joint distribution of BRCA1/ BRCA2 UVs as classified using each method.

Because of the importance of more precisely determining the role played by HLA alleles in PsA, using improved PsA case ascertainment based on the Classification Criteria for Psoriatic Arthritis (CASPAR) [ 1] and more accurate methods of allele determination, we set out to compare the similarities and differences in the frequency of HLA-B and HLA-C locus alleles between PsO and PsA.

As the genetic mixture method provided a clustering solution similar to that described in Vähä et al. (2007), where BAPS was unable to partition MS + HW samples, we utilized the method of 'correlated allele frequency'-model (Falush et al. 2003) implemented in the program STRUCTURE (Pritchard et al. 2000).

Instead of utilizing a Bayesian estimation-based method called site-frequency spectrum (SFS) on population individuals [ 10], we used this SFS to calculate the somatic allele frequency in each SM site of all BC and BN cells respectively, based on the same methods of estimating allele frequencies from reads in one site and additional estimating sample allele frequencies.