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We performed this study to validate a previously derived method of adverse event detection using term searching in physician-dictated discharge summaries.
Second, we recommend an economic analysis to determine the most efficient method of adverse event detection.
Even in acute pain studies, the method of adverse event ascertainment can influence measured adverse event prevalence [ 18].
17 Thus, for those who are interested in improving quality of care in the ED, this modified electronic trigger may serve as a more efficient method of adverse event detection.
While we recognize that this method of adverse event surveillance is biased to differently detect possible adverse events among patients that are randomized into the intervention group, we decided this protocol as a way to quickly detect any safety concerns regarding the intervention.
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Regarding procedures or methods of adverse event surveillance, parameters of interest included; the mode of detection of adverse events, availability of persons assigned to detect, and the existence of clear case definitions of serious and minor adverse events.
The procedures or methods of adverse event reporting was assessed with indicators that verified the availability of persons to report, the reporting target for both expected and unexpected adverse events, existence of a reporting time frame, and reporting procedures.
Assessment of procedures or methods of adverse event investigation were based on indicators that evaluated the procedures of investigation, existence of stopping guidelines, existence of a plan to analyze data on adverse events and the existence of plan to manage serious adverse events.
The Global Trigger Tool GTTT) developed by Institute for Healthcare Improvement, is an objective and retrospective method of detecting adverse events [ 8].
This study suggested that HSP accumulation might provide a method of quantifying adverse biological impacts of exposure to toxicants when examining wild populations from contaminated sites.
14 This instrument is a point scale ranging from 0 to 8, with points derived from the description of randomisation, blinding, inclusion and exclusion criteria, withdrawals and method of assessing adverse events.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com