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In contrast, the Bucher method necessitates a two-step analysis in which we would first need to meta-analyse the results from the two trials of bevacizumab plus IFN vs IFN and then perform the indirect comparison of this pooled result with the result of the trial of sunitinib vs IFN.
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Calculation methods necessitate a simplified empirical formula.
This method necessitates solving a series of simultaneous equations using, for example, Cramer's rule to obtain the component intensities from the measured ones.
The yield line method being a common kinematic approach for the yield design of plates, which enables to obtain upper bound estimates quite efficiently, it is first shown that its extension to the case of complex strength criteria as those calculated from the homogenization method, necessitates the computation of a function depending on one single parameter.
To be fully effective, such a method necessitates substantial information on vector ecology, distribution of breeding sites and local environmental conditions and should be combined with insecticidal adult vector control [100].
The method of analyzing patient- and person-reports depends on the assessment method; a qualitative method necessitates qualitative strategies for analyzing interviews or diaries (e.g., Mayring's content analyses [53]), while for quantitative methods, statistical analysis like t-tests, non-parametric tests, or regressions using a statistics program have to be performed.
This method necessitates that RNA is extracted from a fixed volume of biofluid and samples processed equivalently.
The study of amino acid requirements using an amino acid oxidation method necessitates the knowledge of the degree of retention of labelled CO2 generated during the oxidation of the labelled amino acid.
This numerical method necessitates deep extensions that are detailed herein.
As this method necessitates the beam crosses the sample, it is more demanding in term of sample preparation and requires thin-section preparation.
However, this method necessitates invasive blood sample collection and biochemical examination, which are time consuming and laborious and risk patient injury.
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