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Exact(4)
The overall shape of the spectral function from the XY method is unchanged compared to the exact case.
Using a cut-off of 1.083 the specificity, in comparison with clinical performance measured using the CI method, is unchanged at 83.5%.
When using a cut-off of 0.390 the specificity, in comparison with clinical performance measured using the DP method, is unchanged at 38.5%, but sensitivity is significantly increased from 88.5%95%5% CI 79.7 94.4) to 96.6%, and NPV from 80.8 (95% CI 67.5 90.4) to 93.3% (Table 3).
We stress that in each of our experiments, the function prediction method is unchanged, and does not explicitly incorporate confidence or pathway information in any way, except in that it uses the values from the cDSD, caDSD or capDSD matrix instead of from the DSD (or ordinary shortest-path distance) matrix.
Similar(56)
Specificity using the Southampton method was unchanged across reconstruction and calibration choices (82.4 88.2%).
Comparable sets of experiments were carried out using the top-5% of the rankings to evaluate the various searches; the relative performance of the various methods was unchanged and we have hence included the results only for the top-1%.
The rankings of the methods are unchanged using cross-validated RMS error as the evaluation criterion (See Supplementary Section 10).
The Ca2+ uptake speed, estimated by linear regression from the slope of the ascending phase of [Ca2+]m rise (see Materials and Methods), was unchanged in Afg3l2 −/− cells compared with syngenic controls (Fig. 2A).
We further choose two points (omega=1.9) and (omega=1) as examples to approach two extremal points and (omega=1.4) close to an intermediate point to explain that the IT of the AOR method changes greatly and that of the AOAOR method is almost unchanged for the larger intervals of the parameters ω and γ.
It means that the performance of the U method for different (emptyset) values is unchanged.
The head cutter is unchanged in the proposed method.
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