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We show by theory and simulation that the method is unbiased.
The results show that our method is unbiased for the all range of Eb/N0 values.
As a result, our method is unbiased with respect to prior knowledge about certain genes or pathways.
While this method is unbiased, the minimum spanning tree consists of a relatively low number of connections and may under-represent less strong, but nonetheless important, connections.
Therefore, if the GY method is unbiased in this instance, there should be no difference in the proportion of positively selected sites between the four structure classes (when the simulated data was analyzed by codeml, a program within PAML, to search for positive selection).
The mean error (ME) should ideally be close to zero if the prediction method is unbiased, and the values of this parameter suggested that all predictions generated impartial estimates when evaluated from both prediction and validation sets.
Similar(47)
We ran simulations to test whether the method was unbiased.
The method was unbiased towards neither of the polar or nonpolar metabolites.
The process of deriving all predictions in our method was unbiased by any computational or experimental knowledge.
In a test, this method was unbiased with a mean absolute difference of ±3·3 years between the true and estimated year of death (Metsaranta et al., 2007).
All three methods, being unbiased by definition, show almost no empirical bias of total GVs (results not shown).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com