Sentence examples for method is difficulty from inspiring English sources

The disadvantage of this method is difficulty in detection of multistrain infections and minute changes in sequence that can alter virulence.

One drawback using planar images and CV method is difficulties with high and unpredictable time-dependent activity uptake in overlapping normal tissues and tumors.

The shortcoming of this method is the difficulty of fixing the knife to the target lesion.

One of the main drawback of this method is the difficulty in finding subsystems which verify SEA assumptions.

A limitation of this method is the difficulty of finding an appropriate Cys ligation site in many synthetic targets.

The sole drawback of this method is the difficulty in finding that special structure that can be exploited in certain RA problems.

A drawback inherent in this method is the difficulty in determining the appropriate Lyapunov function to prove the stability This method suffers from the same flaw as the adaptive fuzzy controller.

A remaining weakness in the current implementation of the proposed method is the difficulty for increasing dimensions of parameters due to its high computational cost which prevents to handle more complex lighting environments.

An inconvenience of a validator that does not generalize its validation method is the difficulty in maintaining its code, making unfeasible the adaptation of the validation to other versions or profiles of the language.

Another limitation of the Sanger method is its difficulty in sequencing GC-rich regions.

The major obstacle with this method is the difficulty in distinguishing between benign and metastatic lymph nodes (Love et al, 2005).