Although our method involved initial manual curation of elementary phenotypes, it can be readily generalized to other disease sets with available phenotype descriptions.
The English version was translated using rigorous methods involving initial translation by one party and creation of five possible versions.
As the fluorimetric and HPLC methods involve initial acid precipitation of proteins, the Trp measured is the total Trp.
The method involves an initial extraction of chlorine gas from the water through the air-filled pores of a hydrophobic membrane.
The proposed optimization method involves an initial blank shape, which is iteratively trimmed according to the deep drawing simulations results, to achieve the final optimal blank shape.
Unlike the Delphi method, which generally involves multiple questionnaire-driven rounds to obtain convergence of opinion, the RAND method involves an initial individual rating round, and a second face-to-face round.
In brief, this method involves formulating initial theoretical propositions (or hypotheses), examining the case study evidence, revising the propositions, and examining the evidence once again from a new perspective [ 60, 80, 82, 84].
All these compounds were readily prepared via an elegant multi-step method involving the initial construction of 1-nitro-10H-phenoxazine ring and then fused imidazole ring as key steps.
This method involves, first, identifying an "initial analysis sample" based on appropriately sized sample sizes and second, defining the "stopping criterion" – e.g., how many additional interviews will be carried out with no new themes emerging, at which point data saturation can be declared.
