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Independent determinants of deterioration in glucose tolerance were identified by multivariate Cox method including only covariates for which the P value at a univariate analysis did not exceed 0.15.
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The model is updated using low-rank symmetric updates and other computational requirements of the method include only simple operations such as matrix multiplications and solutions of low-order algebraic linear systems.
A number of similarity metrics are possible; the original definition of the CE method included only structural superpositions and inter-residue distances but has since been expanded to include local environmental properties such as secondary structure, solvent exposure, hydrogen-bonding patterns, and dihedral angles.
The variant method includes only the shortest paths for which both ends are in the input nodes.
This method includes only a smaller part of available information, but selection bias is reduced as much as possible.
Some of the methods include only one or two of the described steps [16], whereas others include all three steps of pyrite pretreatment [12],[12].
However, most current docking methods include only classical interactions.
Depending on their scope, most existing methods include only a subset of the components.
I suggest either adding such explanation (leading to some repetition) or re-organizing the paper so that "Methods" include only very formal description of databases used etc., whereas the description of the algorithm is placed under "Results".
Subsequently, a separate multivariate linear regression analysis was performed for TSK-I, TSK-AA, and TSK-H as dependent variables, using the Backward elimination stepwise method and including only independent variables that show P < 0.250 at the univariate analyses.
This method is identical to that previously described [ 17]; in part, this method was modified from previously reported methods by including only the country of birth of grandparents [ 14, 19].
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