22 NICE recommends use of the TTO method in a representative sample of the UK population, as was the case in this model.
A cross sectional survey was carried out in May 2008, using a stratified sampling method in a representative sample of the Moroccan adult population.
For example, in a guide to technology appraisal methods, the UK National Institute for Health and Clinical Excellence (NICE) advocates direct health-state valuations determined using the TTO method in a representative population sample in situations where EQ-5D™ data are unavailable [ 21].
In these cases, the valuation of descriptions should use the time trade off method in a representative sample of the UK population, with ' full health' as the upper anchor, to retain methodological consistency with the methods used to value the EQ 5D' [ 2].
We attempted to determine the level of knowledge about mechanisms of action of birth control methods in five representative samples of European women.
The primary objective of this study was to compare activity across the two methods in a representative sample of participants who spanned the stroke severity spectrum.
Undoubtedly, it is absolutely essential to critically evaluate diagnostic potential and clinical benefits of such a powerful preoperative imaging technique with standardised methods in a representative group.
However, even when developed using robust statistical methods in large, representative data sources, risk prediction models require validation before they can be used with confidence [ 4].
The aim of this study was to analyse the factor structure of HLOC based on the German modification of the MHLC with up-to-date methods in a representative large western general population sample.
Compared with the simple method of finding orthologs in representative species [ 62- 64], GeneTrace algorithm takes gene loss and horizontal transfer events into account to a certain extent, and thus is more precise in assessing protein ages.
