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All these features of WAC make it a potential method in drug discovery for fragment screening.

Scientific method in drug discovery has centered on generating a hypothesis (target identification) and hypothesis testing (target validation).

Virtual screening (VS) is a widely applied method in drug discovery that is used to predict novel bioactives from large chemical libraries [1 4].

However, the experimental binding mode was reproduced successfully using members of the core ensemble as the docking target, establishing the usefulness of the method in drug design.

To ascertain the nature, and not just the spectra, of all compounds in a given drug, including impurities and degradation products as well as active ingredients, high-performance liquid chromatography (HPLC), considered the current gold standard analytical method in drug analysis, would be required.

Molecular docking is a computationally intensive and prominent method in drug discovery process.

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Drug side effect prediction is one of screening methods in drug discovery.

Some of the most popular and successful methods in drug discovery are structure-based.

The implications of these methods in drug design will be discussed.

To describe the use and reporting of interrupted time series methods in drug utilization research.

The importance of wide application of computational methods in drug discovery processes has been extensively reviewed [48, 49].

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