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The new method, called jointly learnt NMF (JLNMF) method, identifies both distinct and shared TF bases and is able to use the decomposed bases to successfully retrieve and separate the class-specific information from data.
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Each method identified both well established and novel mechanisms of disease pathogenesis, and because the biologic basis of each of the methods is unique, the methods are complementary, with each highlighting a different aspect of the disease.
Synteny block analysis across 23 arthropod species with sequenced genomes (see Methods) identified both Hox and Wnt gene clusters, and highlighted a genomic cluster of TipE gene family members as one of the most conserved blocks of orthologues with well-maintained local gene arrangements.
The biosensor-based direct screening method identifies the interaction of both orthosteric and allosteric ligands with solubilized, native GPCRs, in a label-free and cell-free environment, thus overcoming the limitations of indirect and displacement assay methods.
This method identifies unsafe scenarios that encompass both the technical system flaws and organizational deficiencies and proposes derived safety control measures in these two dimensions.
Results show that the method correctly identifies both single and multiple damages in the structure.
Generally speaking, the proposed method successfully identifies both pleiotropic SNPs at the genomewide level.
In contrast, in addition to detecting aneuploidies, our method explicitly identifies both amplicons and individual genes whose copy numbers are the most discriminative of the clinical label, suggesting specific targets for further biological investigation.
N-ChIP-seq reproducibly recovers Abf1 and Reb1 binding sites with higher specificity and sensitivity than other profiling methods and identifies both previously characterized and novel sites.
That is, the detection method identified the same signal under both geographic constraints.
A recent method to identify both the excitation and flexible support parameters of a rotor-bearings-foundation system has been verified experimentally in this paper.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com