As the objective here was not to reevaluate all existing dating methods against the ones presented here, I focused on the "best" method identified by [33], namely, penalized likelihood (PL).
Our culture method, with high-salt pre-enrichment broth and a second specific broth, was similar to the more sensitive method identified by v. Duijkeren et al. when comparing two methods [ 12].
The methods, identified by economists affiliated with the Poverty Action Lab at the Massachusetts Institute of Technology, offer a splash of good news in an often bleak landscape.
To provide a comparison, we also ran the same enrichment test on the pathways (redundancy removed, see Methods) identified by Kelley and Ideker [1] and Ulitsky and Shamir [8].
As shown in Figure 3 upper panel, the pathways (redundancy removed, see Methods) identified by our method were significantly (P<1e-16, Wilcox rank sum test) larger than that of Kelley and Ideker [1], whereas the sizes of the pathways in Kelley and Ideker [1] was significantly (P<1e-6, Wilcox rank sum test) larger than that of Ulitsky and Shamir [8].
Of the five methods identified by Merriman, three methods are inexpensive to implement, use publicly available data, and are easily employed without specialized econometric knowledge.
Future pre-processing methods, identified by [ 9], apply steam explosion and compressed liquid hot water in order to hydrolyse the cellulose and hemicellulose fractions.
However, because the adaptation of time-series methods to recognize outbreaks will be an ongoing need, the enhanced methods identified by this study are likely to have lasting usefulness.
The Declaration of Helsinki states that: "At the conclusion of the study, every patient entered into the study should be assured of access to the best proven prophylactic, diagnostic and therapeutic methods identified by the study".
In addition, Pearson correlation was used to test the relationship between signal quality, defined as SNR, and accuracy of the onset detection methods, identified by the detection error, ε.
Using a selection of HPV-associated versus smoking-associated features (see Methods), identified by comparing HPV+ with HPV- HNSCC, MDS of the datasets using a simple Euclidean distance measure was applied, and distances were plotted.
