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It is found that this method has substantially outperformed two related ones that use the same supervised protocol to the entire area directly or to the rural subset and the urban subset without being MESMA processed.
Our method has substantially higher power than LOT for the three penetrance models.
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First, driver loci inferred using the linked method had substantially more accurate (higher) selection coefficients than those obtained with the unlinked method.
In comparison to the GRS14, the 3-level haplotype risk method had substantially lower predictive power, with AUC = 0.773 (95 % CI 0.751-0.795).
The results for the models predicting risk of in-patient and six-month mortality showed that the CMS-HCC method had substantially higher discrimination than the other two risk adjustment methods when we included the index admission claim in coding the risk adjusters.
Recent development of molecular methods has substantially improved the identification of many bacterial pathogens, both at the species and strain levels.
In past years much progress in developing molecular-based methods has substantially led to new insights into mechanisms of action of immunosuppressive and/or immunomodulating remedies including biologics.
In the last 50 years, the introduction of screening methods has substantially reduced the incidence of cervical cancer in the industrialised world.
As a result, there are many questions in respect of the mechanisms of action of dapsone that remain to be addressed: In past years much progress in developing molecular-based methods has substantially led to new insights into mechanisms of action of immunosuppressive and/or immunomodulating remedies including biologics.
Over the past two decades, microarray-based methods have substantially improved our ability to quantify gene transcription through gains in throughput.
In recent years, graphical methods have substantially expanded the medicinal chemistry repertoire for analyzing Structure-Activity Relationships (SARs).
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