In addition, the greater sensitivity and specificity of this assay method has permitted the detection of episodes of fetal loss not detected by radioimmunoassay of urine specimens.
The RTI-TMA method has amply confirmed the earlier studies by Fenstermacher and colleagues using sucrose or inulin; however, the RTI method has permitted studies with much higher spatial and temporal resolution so that, for example, anisotropic [ 22] and inhomogeneous properties [ 23] could be determined and the behavior of the ECS quantified in ischemic tissue.
In turn, the development of radiometric dating methods has permitted numerical estimates of age to be incorporated in the scale of geologic time.
In addition, the adoption of continuous miner and tunnel bolting support methods has permitted improved development rates to be achieved at the cost of increased emissions of dust, gas and heat and humidity.
Over the centuries, developments in synthetic materials, surgical techniques, and sterilization methods have permitted the use of biomaterials in many ways [2,3].
Advanced imaging and characterization methods have permitted the 3-D and phase-specific reconstruction of dense and opaque samples with features that have a length scale on the order of tens of nanometers and comprised of materials with large X-ray mass absorption coefficients.
The results obtained with these methods have permitted to highlight why a-CN0.30, the a-CNx sample with the highest nitrogen content among those investigated in this work, behaves both as a dielectrical material (low electronic conductivity) and as an ideally polarizable interface (high polarization resistance).
Molecular typing methods have permitted investigation of the outbreaks [ 36, 61, 100, 139, 165, 166, 213, 214], discrimination between exogenous reinfection and endogenous reactivation [ 209, 210, 215– 217], identification of mixed infections [ 215, 218, 219], and cases of misdiagnosis due to laboratory contamination [ 220– 220].
Quantitative targeted absolute proteomics (QTAP) represents a new generation of proteomic methods that has permitted the determination of absolute protein expression levels (mol) of target proteins in biological materials by liquid chromatography-linked tandem mass spectrometry (LC-MS/MS) [ 4].
By using both quantitative and qualitative methods, this study has permitted more in-depth analysis of the effectiveness of this PPP model.
The development of synthetic methods and supramolecular chemistry has permitted access to carbon-based nanoparticles such as fullerenes and metallic (e.g. Au, Ag, Pt), semiconducting (e.g. CdSe, CdS, ZnS, GaAs), magnetic (e.g. Fe3O4), polymeric and hybrid (e.g. core shell) nanoparticles.
