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This is particularly important in drug discovery and the computer-aided drug design (CADD) method has identified molecules modifying protein-protein interactions as potential drug candidates [8, 9].
The use of the PANTHER analytic method has identified the Alzheimer's disease/presenilin pathway to be the most severely dysregulated pathway in the HPRT knockdown cells (Table 2).
The results (Figure 4) show that our method has identified proteins involved in cell adhesion, matrix/membrane organization, cell proliferation and differentiation as potential substrates.
Our method has identified many more HI and HP genes than have been reported previously.
Moreover, the present method has identified correctly optimal pathways for pentose phosphate and glycolytic pathways.
This method has identified arrays of conserved sequence blocks in NCS of vertebrates from fish to humans [ 16, 17].
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Although some sRNAs identified in the deep sequencing contain Rho-independent terminators, it was not clear whether the RNA-seq method had identified all sRNAs that possess Rho-independent terminators.
Although several studies using the RAND appropriateness method have identified sets of 'valid' indicators, their value and feasibility for change is not usually assessed in terms of the extent to which they identify patients with actual inappropriate prescribing.
Each of these methods has identified interesting candidate substrates, some of which have been validated using various biochemical tests.
Recent work in England using time-series methods has identified associations between numbers of weekly reports of laboratory-confirmed infections with Campylobacter, M. pneumoniae and influenza, and incidence of hospitalization for GBS in subsequent weeks [24].
The use of multiple methods has identified numerous factors that warrant further investigation in Tunisia and other similar low/middle income countries.
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CEO of Professional Science Editing for Scientists @ prosciediting.com