Therefore, a method for conferring selectivity on the compounds is essential if they are to be considered as potential trypanocides.
In this study, we proposed a method for target selectivity evaluation and compound promiscuity identification by analyzing the biological test results in PubChem.
The proposed method was assessed for selectivity, linearity, precision, accuracy, and stability.
The optimized method was validated for selectivity, linearity, limits of detection and quantification, recovery and precision.
The method was validated for selectivity, carryover, sensitivity, extraction recovery, matrix effects, linearity, accuracy and precision, dilution integrity and stability studies.
The optimised method was validated for selectivity, linearity, matrix effect, limits of detection and quantification, trueness, and precision, and then applied to commercial samples of polished rice.
This method was validated for selectivity, linearity, accuracy and precision, extraction recoveries, matrix effects, carry-over, cross-talk, dilution integrity, stability and incurred sample reanalysis (ISR).
The developed method was validated for selectivity, linearity, precision, accuracy, recovery, limit of quantitation (LOQ), and limit of detection (LOD).
The method was validated for selectivity, sensitivity, linearity, precision, accuracy, process efficiency, dilution integrity, matrix effect, re-injection reproducibility, and stability of LS during both short-term sample processing and long-term storage.
The method was tested for selectivity, sensitivity, linearity, accuracy and precision, and proved to be suitable for routine qualitative and quantitative analysis of levodopa, carbidopa, entacapone and their impurities in their mixture.
