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Since it was not possible to define adequate cut-off points for the result of a responsiveness study, a positive rating was allocated when a suitable method for responsiveness had been used.
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Change scores: A crude method for assessing responsiveness is to calculate 'change scores' for the instrument (ie, subtract score at visit 1 from the score at visit 2) and to examine the correlation between this value and a change score derived from another relevant clinical measure.
Due to the lack of consensus on the single, best method for determining responsiveness [ 19], we used a combination of approaches to try to assess whether the RSDI is sensitive to meaningful changes in other measures that should correlate with HRQL.
Methods for fluid responsiveness assessment were classified according to their accuracy [area under the receiver operating characteristics curve (AUC)].
Thus, our primary objective was to perform a systematic review addressing the available methods for fluid responsiveness assessment in spontaneously breathing patients.
The objective of this review is to summarize recommendations on methods for evaluating responsiveness and minimal important difference (MID) for patient-reported outcome (PRO) measures.
Echocardiography is a well-established method for evaluating fluid responsiveness [5, 8, 9].
In this regard, the PLR maneuver has been proposed as a reliable method for predicting fluid responsiveness, challenging the cardiovascular system to a reversible and transient increase in cardiac preload by mobilizing venous blood contained in the lower limbs and abdominal compartment toward the intrathoracic vessels.
Considering all dynamic parameters described here, the use of any method for predicting fluid responsiveness was possible in 15.6% of the volume expansions performed in our ICU.
A recent study demonstrated that pulse pressure variation (PPV) ≥16% has provided an accurate method for predicting fluid responsiveness in pediatric congenital heart surgery.
Concurrent with collection of measurements using the DEMMI, HABAM and BI, data were also gathered using a global rating of change (GRC) scale to provide a method for estimating criterion based responsiveness and the MCID.
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