Sentence examples for method for mutation from inspiring English sources

Our goal was to develop a novel, reliable and rapid genotyping/scanning method for mutation detection of the exon 20 of the BRCA1 gene, using high-resolution melting curve analysis.

178 DGGE is a rapid, commonly used method for mutation detection.

HRM has recently been introduced as a screening method for mutation detection.

Thus using minimum variance multiplier will be a more sensitive method for mutation prediction with multi-copy sequences.

High-resolution melting (HRM) curve analysis has proven to be a highly sensitive method for mutation discovery and SNP genotyping [ 22].

This will provide further insight into the true sensitivity of HRM and applicability of the method for mutation scanning of the entire coding regions of BRCA1 and BRCA2.

The advent of highly sensitive methods for mutation detection raises a provocative question whether any mutation detected should preclude the use of cells in various in vitro applications and particularly in potential therapies.

Recent major advances in the EGFR field include the discovery of EGFR somatic mutations in NSCLC that have important implications for biology, treatment, clinical trial design, and methods for mutation detection.

Compared with other published experimental methods for mutation analysis, the translation initiation can not be disturbed by multiple bases mutations using the proposed method, which shows the effectiveness of this method in improving the translation efficiency and its biological relevance for genetic regulatory system.

Sensitive methods for mutation detection in clinical specimens have been developed that enable patient selection for genetically informed cancer therapy [4], [5].

Consequently, robust, reliable, and sensitive methods for mutation analysis are required to stratify patients eligible for anti-EGFR therapy.