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Unsupervised clustering and heatmap generation with sorted datasets, using Pearson's correlation in Ward's method for linkage analysis, were performed using Partek Genomics Suite 6.6.
A classification scheme using Euclidean distance for similarity measurement, together with Ward's method for linkage, produces the most distinctive groups.
The similarity measurement, together with Ward's method for linkage (Ward 1963), produces the most distinctive groups where each member within the group is more similar to its fellow members than to any member outside the group (Güler et al. 2002; Belkhiri et al. 2010).
We have developed a Bayesian method for Linkage analysis of Ordinal and Categorical traits (LOCate) that can analyze complex genealogical structure for family groups and incorporate missing data.
We used Ward's method for linkage and Pearson's correlation for distance metric.
Cluster analysis will be used to group data (hierarchical approach using Ward's method for linkage).
Similar(51)
In this review, we summarized the recent methods in QTL identification, including novel statistical methods for linkage and association mapping, special population types, and whole-genome sequencing.
Bayesian methods for linkage analysis are useful because they allow for incorporation of prior information about allele frequencies, meiotic drive, and other factors important to linkage calculations.
We therefore sought to develop more efficient methods for linkage mapping in this parasite.
Detailed methods for linkage group construction and marker selection were described in [ 33].
Improved methods for linkage and guidelines for evaluating and handling linkage error will help improve the reliability and validity of results based on linked data [ 36, 37].
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