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The AGREE II instrument is an accepted method for appraising clinical guidelines.
> -wrap-foot> There is less agreement on the most appropriate method for appraising qualitative research (Walsh and Downe, 2006).
Randomised controlled trials have been described as the best method for appraising a causal relationship between a complex intervention and clinical outcomes [ 12].
This proposed method for appraising and summarising MVHT harmonises with the Cochrane Collaboration's technique for assessing risk-of-bias for internal validity.
The NHMRC therefore created a working party of clinical practice guideline developers, health technology assessment producers and methodologists (the Working Party) to develop a revised hierarchy of evidence for individual studies (first stage) which addressed these issues, as well as a method for appraising the body of evidence (second stage) that could be used by guideline developers and others.
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Senior Doctor Interviewees also noted that following established methods for appraising the quality of guidelines before adapting them was also very time consuming.
Increasing numbers of qualitative studies have led to a demand for reliable methods for appraising and synthesising qualitative research similar to the systematic review and meta-analysis of quantitative studies [ 15, 16].
To apply a new method of appraising the cost efficiency of preventive interventions for the purposes of making such interventions comparable and to facilitate return-on-investment estimates.
However, the recent development of guidelines for good reporting of mixed methods studies [ 7] as well as criteria for appraising mixed methods studies [ 13] might help to improve reporting of mixed methods studies and therefore the potential for their inclusion in systematic reviews.
Furthermore, while there is growing interest in the conduct of MTC and the value of resulting data for clinical decision making, there is currently no established method of appraising and presenting the quality of MTC estimates.
A big source of the discrepancy in valuation is the method of appraising stock options.
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