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During the initial method development, a variety of experimental conditions were screened.
For method development, a panel dataset of 20 images was manually chosen from a dataset of hundreds of water quality images acquired by users.
Prior to method development a target subset of pesticides was chosen to reflect the typical range of chemicals commonly used in previous treatments.
One way to compensate for these issues is to employ, in the early stages of the method development, a device generating reproducible fingermarks.
During the method development, a standard solution of 39 compounds was used for the determination of the respective Relative Response Factors (RRF) employing statistical methods, ANOVA and WLSLR, for verification of the data.
During method development, a wide range of chromatographic conditions and structurally related positional isomer probe molecules were exploited in an effort to gain insight into the specifics of the separation mechanism.
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Moreover, no suitable reference dataset is available to allow for method evaluation and method development in a supervised machine learning approach.
In order to enable non-programming biologists to benefit from the method development in a timely manner, we have created the Chipster software.
In order to enable experimental biologists to benefit from the method development in a timely manner, we have created the Chipster software [ 2].
Method development utilized a high-throughput orthogonal-array-optimization, and two sensitive and stable signature-peptides (SP) from different domains were selected based on extensive evaluations in plasma matrix.
The metal ion content in beverages has been determined in several studies for consumer protection against contamination, method development or an evaluation of the nutritional status [12 15].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com