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The training algorithm consists of three steps: partitioning of the input output space using a fuzzy clustering method; determination of parameters of the consequent part of a rule from over-determined batch least-squares (LS) formulation of the problem, using singular value decomposition algorithm; and adaptation of these parameters using recursive least-squares method.
In the proposed method, determination of fuzzy relations is performed by estimating the optimal fuzzy relation matrix.
These are grounding methods: determination of the thermal conductivity (hot wire method), determination of microstructure, determination of the mechanical properties, determination of absorption and determination of permeability.
The process design is composed of three main steps, i.e. simulation step, conceptual design step (extended Pinch design method, determination of promising modifications, their assessment, selection of the most promising modification) and rigorous design step (structural and parameter optimization).
The artificial intestinal fluid (AIF) was prepared according to the "Official Method – Determination of the Disintegration Time of Tablets" by Health Canada (1989).
Muscle strength was assessed by an objective method: determination of the maximal isometric strength of the ankle dorsiflexers, knee extensors, and hip abductors on both legs using a hand held dynamometer – the Nicholas Manual Muscle Tester (NMMT; Lafayette Instruments, Lafayette, IN). 26 One experienced technician (BK) performed all strength assessments on 53 elderly women.
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By using this method determinations of the curve parameters will not be influenced by intra-and/or inter observer reliability.
Intracellular metabolite concentrations were determined by anion-exchange chromatography after sample preparation (see Methods, Determination of intracellular metabolite concentrations).
Genotyping calls were made as described in Methods, (Determination of Genotypes, Real Time OCP ligation/ERCA).
In both methods, determination of percent inhibition of parasitemia is the most reliable parameter.
Lignin and carbohydrates were analysed according to the National Renewable Energy Laboratory Laboratory Analytical Procedure NREL LAPP) methods (Determination of Structural Carbohydrates and Lignin) [ 25].
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