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The within-chromosome-arm segmentation method detects closely matching changes on several chromosome arms; that is, 5q, 7p, 9q, 10q, 11q, and 16p.
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The BLASTX-aided method detects ORFs by finding the starting methionine and stop codon in catfish transcripts relative to the same features in the most closely related species identified by BLASTX.
"This new method detects cataracts even before they can be detected normally, and before they are symptomatic," he notes.
Since a recent survey found 23% of species reported in the literature to be either poly- or paraphyletic at the various loci investigated [ 10], a sensitive delimitation method should be capable of detecting closely related species at an early stage of lineage divergence, when most of their genetic loci have not yet reached reciprocal monophyly.
The success of structure comparison methods can be measured based on their effectiveness in detecting closely and remotely homologous proteins (Taylor et al., 2001).
Common methods such as ELISA with antibodies for a specific virus, PCR or microarrays with primers designed for a specific virus, or PCR with degenerate primers that amplify a closely related group of viruses are effective methods for detecting close relatives of known viruses [15], [16], [17].
The events detected closely matched the periods of previously reported long-term SSEs.
Therefore, the synthesized sequence has a good capability of separating and detecting closely spaced targets.
Methods that detect constant or extreme biclusters generally outperformed other methods detecting more complex bicluster patterns.
Here we found that, except for some pattern-based biclustering methods, most biclustering methods detected the type of modules, which they are designed to detect (Supplementary Fig. 24).
Current drug testing methods detect drug residue, rather than impairment.
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