Sentence examples for method demands large from inspiring English sources

However it also notes that games and stickers won't work for social messaging's smaller fish — arguing that this monetisation method demands large user-bases to generate the required revenues.

The DVI method demands time-consuming verification.

Scientific method demands that!" Yeah, right.

There is a tension between the theoretical demand that specific types of crime be examined separately (at least until it has been demonstrated that they have the same pattern) and the pragmatic methods demands of examining a sufficiently large number of events that patterns can be detected.

Until recently, affinity chromatography based methods for the isolation of transcription regulators demanded large amounts of samples (e. g. cell-free extract proteins) and/or laborious pre-purifications steps (e. g. heparin-sepharose purification (e. g. [ 35, 36])).

A couple of recent methods predict contact map by using mutual information, taking into consideration contact correlation and enforcing a sparsity restraint, but these methods demand for a very large number of sequence homologs for the protein under consideration and the resultant contact map may be still physically infeasible.

These studies often demand large numbers of cultured endothelial cells, thus justifying the interest in developing reliable and reproducible methods for isolation and culture of endothelial cells that could retain the functional properties of their in vivo counterparts.

They often demand large upfront fees.

Previous ensemble methods demand vast memory spaces and heavy computational burdens in dealing with large-scale datasets, which leads to the inefficiency for the problem of classification.

Larger incomes demand larger expenses.

These customers are demanding larger discounts.