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The Simulated Annealing (SA) scheme is a stochastic method currently very popular for difficult optimization problems.
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Because of these features, PCR methods are currently very popular in the study of MOOPs (Srinivas and Deb 1994; Knowles and Corne 2000; Van Veldhuizen and Lamont 2000; Deb 2002; Jones et al. 2002; Lei and Shi 2004; Konak et al. 2006).
These methods are currently very useful as an adjunct to other approaches mentioned in this review.
The manuscript could be shortened, or perhaps restructured by moving the less central content to the (currently very short) Methods section.
It would be nice to also compare predicted DFE inferred using the two very different approaches discussed in this review; however, direct comparisons of the DFE of mutations inferred by experimental evolution methods and genome polymorphism data are currently very difficult.
Traditional methods of chemical and enzymatic synthesis are effective but are currently very expensive when large amounts are needed.
Currently, very limited information is available in the literature about the methods to be used for designing RC elements manufactured with recycled concrete aggregates.
Currently, very low homology recombination is accomplished by the iterative-truncation family of methods [ 32- 34] or by oligonucleotide-directed shuffling [ 43- 45], because DNA shuffling cannot successfully recombine genes with very low levels of nucleotide identity below about 50%.
Nevertheless, especially for very sensitive, specific, and reproducible analyses of limited numbers of proteins, this strategy may be the best method currently available [ 40].
Vasectomy is considered one of the most reliable family planning methods currently available with very low post-vasectomy pregnancy rates.
Currently, very few models are available for these purposes.
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