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Unbiased estimates of the associated P-values were calculated using the Markov chain method computed by genepop version 3.4 (Raymond and Rousset 1995).
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Importantly, the usual degrees of freedom (DoF) used in common GLM methods computed by ((I-{mathrm {rank}}({mathbf {X}}))) [46] are likely to overestimate the statistic [44] because large statistical values are computed inaccurately when long time-series data are analyzed.
Consistency for a particular scoring method was computed by applying either the manual or automated scoring method to read the same study four times.
The latter method was computed by Multilocus 1.3.b (Agapow and Burt, 2001).
Finally, the mean rank of each method is computed by averaging its rank over all 2000 tests.
The final score of a method is computed by averaging the sensitivities at seven false positive rates (1/8, 1/4, 1/2, 1, 2, 4, and 8 false positives per image).
To identify significant enriched biological processes (p values lower than 0.05), the hypergeometric distribution and the false discovery rate (FDR) correction method were computed by GeneCodis, as statistical analysis.
The relative bias and the mean square error (MSE) of each method were computed by E[(ĉ. − c)] and E[(ĉ. − c)], where the expectation was meant to be the average over the N simulated samples.
The method computes the sensitivity by constructing a Lagrange function.
This procedure, denoted Lagged Diffusivity method, computes the solution by lagging the diffusion term.
Our method computes viscoelastic fluid behavior by supplementing the basic Navier Stokes equations with additional terms for elastic body forces.
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