The methods cited in the patent might give too many clues about what Google is doing next.
Some are more desperate than others: around 40% of AstraZeneca's total sales, for example, come from a single drug, Losec, whose American patent is scheduled to expire this year.Apart from the dubious methods cited in the lawsuits, drug firms have a variety of legal means to spin out their patents in America.
In fact, the main difference between the various methods cited in the references above lies in the method of mass functions estimation and in its application.
To demonstrate the effectiveness of TPMIP, it is applied to eight test systems and the simulation results are compared with those obtained by the existing methods cited in this paper.
Most 3D key-frame extraction methods cited in this paper were developed for specific content and 3D format and only four of them include comparisons with similar methods [18, 22, 41, 51].
Various methods cited in literature for its determinations involve, spectrophotometry [4],[5], spectrofluorimetry [6], atomic absorption spectrometry [7], conductometry [7], voltammetry [8], high performance liquid chromatography- ultraviolet (HPLC-UV) [9]-[11], HPLC-fluorescence (HPLC-Fl) [12]-[14] capillary electrophoresis (CE) [15],[16], and HPLC-mass spectrometry (HPLC-MS) [17],[17].
Most of the methods cited in this paragraph use models that depend on structural properties of the peptides and the peptide-protein complex.
The methods cited in the above review have some advantages and disadvantages depicted in Table 1.
With clear images and fixed and controlled artifacts most of the alternative fitting methods cited in this paper should find the boundary without problems.
For example there are a number of methods cited in this paper including several non-parametric approaches, a variance-stabilizing transformation and Bayesian approaches that could have been compared with the authors' method of choice.
