In addition, good correlation (R2=0.81) between maximum diameters obtained from this method and pathology was observed (Table 2).
These results correspond with those of previous studies [4, 13], in which small differences in maximum tumour diameter between an adaptive threshold method and pathology were reported [13], as well as good correlation between maximum diameters obtained from a percentage threshold-based method and pathology [4].
Here, we describe the usual forms of drug-associated ILD and methods of diagnosis and pathology.
Using a rapid case ascertainment method with the Alberta Cancer Registry and pathology reports, 549 incident, histologically confirmed, primary endometrial cancer cases were recruited.
Apart from conventional screening methods such as imaging and pathology, the molecular diagnosis of NSCLC is becoming increasingly important [ 2].
Information on cancer incidence was obtained through population cancer registries, or via a combination of methods: health insurance records, cancer and pathology registries, and active follow-up (France, Germany, Naples, and Greece).
Fixation of tissue specimens in formaldehyde is a commonly used method in pathology laboratories and in brain banks, being the principal source of human brain samples for research studies (i.e. immunohistochemical studies in free-floating sections).
Detection of p53 protein by immunohistochemistry has become a routine method in pathology practice, and the presence of detectable p53 protein is an important prognostic marker that correlates with higher histopathological grade, increased mitotic activity, aggressive tumour behaviour and therefore a worse prognosis [ 15, 16].
For additional details on subjects, data collection methods, liver pathology, and statistical analyses, see supplementary Methods in the online appendix.
Within the EPIC cohort, as in most other studies, the classification of breast cancer as receptor-positive and -negative (ER, PR or joint ERPR) is based upon a variety of laboratory assay types and quantification methods, reflecting pathology practices across Europe and time.
Assay of formalin-fixed paraffin-embedded (FFPE) tissue samples is a standard method for pathology examination as it is cost effective and ideal for preserving cell morphology [ 1].
