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QSAR models have been validated internally [using leave-one-out cross-validation method] and externally [using test set molecules] to ensure the predictive capacity of the models.
We utilized health insurance claims data covering ~85% of the total population with the objectives to (1) assess VC of all recommended childhood vaccinations in birth-cohorts 2004 2009, (2) analyze cross-sectional (at 24 and 36 mo) and longitudinal trends, and (3) validate the method internally and externally.
Instead, let's have an exam system based on university methods – internally marked and externally validated and moderated on criterion referencing by chartered teacher examiners.
The nomogram was validated internally by bootstrapping-method (200 repetitions) and externally in independent validation set (n = 34).
That means there need to be separate methods to expose data internally and externally within your enterprise (i.e., across business units), and between your enterprise and others as well.
From the standpoint of the strengthening technique, the specimens were categorized into two groups: six specimens were strengthened by Externally Bonded Reinforcement (EBR) method and the other six specimens were strengthened using Externally Bonded Reinforcement on Grooves (EBROG).
Inflammatory markers were assessed using internally and externally quality-controlled standard methods.
This model was both internally and externally validated using the LOO method by calculating statistical parameters which are critical requirements for a model to be robust.
The performance of the pathway-level aggregation methods was assessed by classification accuracy validated both internally and externally, and by correlation of pathway signatures.
Performance of the methods was assessed by classification accuracy validated both internally and externally, and by examining the correlative extent of pathway signatures between the dataset pairs.
That we observed common patterns across two very different tasks (self-induced and externally generated emotion) also suggests a new method for measuring emotion.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com