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Malignancy-level data will include histology, stage, primary tumour site, laterality, metastatic sites, diagnostic method, and disease status (relapse, progression) (Table 2).
Further, recall bias was avoided by the objective exposure assessment method, and disease status could not have biased exposure assessment because adipose tissue was obtained and frozen before cancer diagnosis.
CMD-MMP-9 levels were significantly elevated in the first hours of neuromonitoring in patients who lost consciousness at ictus (P = 0.005), H&H grade 5 patients (P = 0.002), and patients with initial brain tissue hypoxia (P = 0.03) after adjusting for probe location aneurysm repair method and disease severity as appropriate.
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Survival curves were generated by the Kaplan Meier method, and disease-free survival (DFS) rates were compared by the log-rank test.
The PTP is an example of the FDA proactively developing test methods and disease surveillance methods geared toward protecting the public's health.
This chapter provides an overview of the structure, replication and biology of these viruses with a particular focus on YHV disease characteristics, diagnostic methods and disease prevention strategies.
There is a significant correlation between the degree of synovial inflammation as documented by gray scale and power Doppler methods and disease activity indices [ 28].
The measures are seen as methods of capturing patient's opinions and feelings regarding their disease and treatment, their perceived need for healthcare and their preferences for treatment methods and disease outcomes.
However, the heterogeneity of methods and disease states in the review precludes any generalisable numerical summary of effect size that would apply to a different spectrum of patients or methods.
We initially considered using PCA to accomplish this goal but observed that the first PC was correlated with both collection site (see Methods) and disease status, which often occurs whenever different sites have differing fractions of cases and controls.
The extracted data included specific details about the geographical context, study methods and disease focus [see Additional file 1: Table S6], elements included in the intervention, study participants, and outcomes of significance to the review questions [see Additional files 1: Table S7 Table S7 Table
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