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All this was packaged into Carnegie's systematic method, an important key to his popular success.
As compared to the solid finite element method, an important saving in computational cost is achieved.
Regarding application of this latter method, an important challenge to trained phage use is the time elapsed between obtaining the bacterial sample for production and actually applying the trained phage to the site(s) of infection.
As discussed in the section on the estimation procedure method, an important advantage of our proposed approach is that the parameters in the multi-state model may conveniently be computed using a semi-parametric or parametric approach with an existing R package FrailtyPack for frailty models.
In the following, we shall enumerate briefly the main experimental problems of this method: An important problem that needs to be taken into account is the resolution of the energy of the primary beam.
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In the above-mentioned methods, an important step is extracting certain important information from the speech signal.
Regarding factorization methods, an important issue to take into account is the initialization/constrain of the parameters.
All the above makes prediction of enzymatic function with computational methods an important alternative approach.
Without specific information on responsiveness and correlation between methods, an important additional source of heterogeneity may be introduced.
Spearman rank correlations reflect consistency in variety rank between methods (an important criterion for plant breeders) and are less influenced by individuals at the tails of the distribution.
With all modelling methods an important part is the selection (and the number) of prognostic variables to be included in the model.
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