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Following a similar weighting scheme implemented in SNPs&GO [Calabrese et al., 2009], our weighted/species-specific method amalgamates sequence conservation within the HMMs with "pathogenicity weights" representing the relative frequencies of disease-associated and functionally neutral AASs mapping onto conserved protein domains.
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Supertree methods amalgamate trees containing information from different, but overlapping, relationships into a larger supertree (e.g., [ 1]).
That the difference was greater than ours can be partly explained by the limitation of meta-analysis when studies use different volume cut-off categories and adjustment methods and amalgamate studies from different healthcare settings.
By amalgamating the X-ray diffraction technique with the grain boundary tracking technique, a novel method, diffraction-amalgamated grain boundary tracking (DAGT), has been developed.
The method illustrates further the advantages that accrue by amalgamating flow and batch methods of synthesis.
A standardized method of scoring the goal attainment scale, and of amalgamating several goals into one overall score, has been devised and provides a measure of the overall success of the program or project.
However the principles upon which the two methods are based are not entirely different; the supertree approach amalgamates information from the distance matrices produced using each of the 22 Archaea as the conditioning genome.
They still use ancient techniques, like the luxurious kundan method, using paper-thin sheets of gold folded in on themselves and amalgamated.
Researcher and participant reflections were then amalgamated to consider the practical and logistical advantages and limitations of each method.
The supertree approach seeks to amalgamate the information from many input trees and therefore is a sequence-based method that is more democratic in terms of getting its information.
Mercury amalgamates, or mixes, readily with many metals.
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