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This method allows direct measurement of the protein activity without protein purification steps (Ueda and Tanaka 2000).
Moreover, by providing force-dependent dissociation rates this method allows direct testing and validating of any energy landscape model.
The method allows direct calculation of wall shear stress and flow rates generated by pulsed flows, which are of interest in fouling mitigation and cleaning-in-place systems.
Our method allows direct comparison of single mitotic chromosomes with their daughters in interphase.
Our network meta-analysis, which applies a transparent method, allows direct and indirect comparison of all currently used antimuscarinics, dosages, formulations and routes of administration.
The toeprinting method allows direct assessment of ribosomal binding to the mRNA obviating the complexities of various post-translational steps involved in generating pMHC I [33].
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In particular, without chromatographic separation, the method allowed direct FAs profiling in complex samples due to the advantageous priority of DMPP in signal enhancement as well as the extra resolution that IM MS offered.
We have further developed and refined a telomere PCR approach, which was rarely used previously (mainly in specific telomeric projects), into a robust method allowing direct visualisation of telomere length differences in routine experiments with S. cerevisiae, and showing a strong correlation of results with data obtained by Southern blot hybridization.
This closed population method allowed direct comparison of population estimates from our data and those from the study by Dovel et al. [16], [23].
This method allowed direct quantitative comparison of the phenotypic variability of our samples.
These printing methods allow direct printing of any kind of arbitrary, two-dimensional shapes including patterning of the electric contacts and thus no post-patterning stages are needed.
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