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The optimized method allowed quantification of T6P in plant extracts with good linearity (r > 0.99) within a biologically relevant concentration range.
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This HPLC method allows quantification of theophylline and paracetamol in milk matrices and it can be applied in the design, development and production of milk-based pediatric dosage forms.
Clinical evaluation of a colchicine specific antigen-binding fragment (Fab) in order to treat colchicine poisoning required the development of an accurate method allowing quantification of free and Fab-bound colchicine in plasma and urine, and free colchicine in tissues, to measure colchicine redistribution after Fab administration.
Because the SERS nanoparticles have a gold core of defined size, this method allows quantification of intratumoral SERS nanoparticle uptake.
This method allows quantification and determination of cellular origin via the use of specific fluorescent antibodies and calibration beads.
This method allows quantification of cells in hot spots defined in this study as areas containing the highest density of positive cells.
Although our maximum likelihood estimation method allows quantification of all possible interactions of a target protein, we still do not know the significance of the interaction and whether it can be regarded as a true interaction.
The purpose of the work was the development of a PVE correction method allowing quantification of glucose metabolism in tumour cells with the primary objective to be easily implementable and usable in a clinical environment.
Our results demonstrate that SE-HPLC analysis using a high-resolution column in combination with suitable aggregate standards can be a valuable tool to determine aggregate formation in cell culture, as the method allows quantification of mAb aggregate content within 20 min directly in the cell culture supernatant without falsifying the results by labor-intensive pre-purification of the samples.
The use of d10-phenanthrene as internal standard not only improved the repeatability of the method but allowed quantification of the samples against external aqueous standards.
The method allowed drug quantification in fresh and powdered milk with a relatively short run time of analysis and it was also successfully applied to the quantification of the drugs in solid dosage forms intended for pediatric use.
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