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In the proposed method, a limit value is defined for each particle, and if the particles could not improve self-solutions at the end of current iteration, this limit is increased.
By using this method, a limit of detection of 0.15 fmol (on-column) was obtained for both CpopC-1 and CpopC-2.
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Consistent with this, Moldoveanu and Gerardi [16], using an analytical method with a limit of detection of 12 ng/g, failed to detect acrylamide in uncured dried tobacco.
This SPME-GCMS method afforded a limit of detection and quantification of 1.54 and 5.13 pg, respectively.
The described method provided a limit of detection and a limit of quantification of 1.3 × 10−8 M and 4.0 × 10−8 M, respectively.
Under optimized conditions, the method presented a limit of detection of 0.11 μg L−1 and linear analytical curve from 1.0 up to 50.0 μg L−1 (r = 0.993).
For most targets this method has a limit of detection (LOD) of 0.1% or less.
The method has a limit of quantification of 10 ng ml−1 and an intra-day and inter-day precision and accuracy within±10%.
This assay method has a limit of sensitivity of 10 pg ·mL−1 for epinephrine and the inter- and intra-assay variation were less than 3%.
That produced by the colorimetric methods (A) limited the measurement to the levels excreted by post-menopausal women and men (∼3 µg/24 h).
As an improvement to the calculation method, a combined limit of current and voltage is proposed to obtain results that are more reasonable.
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