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Pinealectomy enhances tumor growth and metastatic spread in experimental animals.
Metastatic spread of tumour cells is the main cause of cancer-related deaths.
Li, X. et al. VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread.
We also tested an orthotopic model focusing on the metastatic spread.
Mst1r promotes the metastatic spread of breast carcinomas by subverting antitumor immune responses.
MMP3 is a matrix-metallo protease contributing to initiate the metastatic spread in various tumours55.
Tumor-infiltrating immune cells can promote chemoresistance and metastatic spread in aggressive tumors.
Such studies may lead to new ways to intervene in metastatic spread.
Tied to these advances and increased survival, however, have been new patterns of metastatic spread.
Growth and metastatic spread of invasive carcinoma depends on angiogenesis, the formation of new blood vessels.
The inhibition of receptor tyrosine kinases can inhibit both tumour growth and metastatic spread.
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