Sentence examples for metastatic phenotypes in from inspiring English sources

Relative to Epi-type cells, an increased abundance and distinct localization and activity signature of the receptor tyrosine kinase AXL were associated with metastatic phenotypes in Mes-type cells.

Second, surprisingly our initial experiments demonstrated that 200 mM methyl sulfone induced contact inhibition and therefore might prevent progression of the disease by inducing more normal phenotypes and fewer metastatic phenotypes in melanoma cells.

Increasing evidences implicated the role of JWA on oncogenic and metastatic phenotypes in several human cancers.

Pre-clinical studies strongly support the hypothesis that collagens and fibronectin directly promote metastatic phenotypes in cancer cells.

Copy number increase (CNI) of ACTN4 has been associated with poor prognosis and metastatic phenotypes in various human carcinomas.

Overexpression of Stathmin and low levels of p27 for example, contribute to the metastatic phenotypes in human sarcomas.

Melisi, D. et al. Secreted interleukin-1α induces a metastatic phenotype in pancreatic cancer by sustaining a constitutive activation of nuclear factor-κB.

Yang D, Thangaraju M, Greeneltch K et al. Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells.

Thus, this work indicates that there is a specific association of ACT overexpression with the metastatic phenotype in our breast cancer metastasis model.

Consistent with the previous reports6,12 which demonstrated induction of tumorigenesis and metastatic phenotype in EDA transfected cancer cells, it was observed that transient expression of EDA significantly increased the migration and invasiveness of T47D cells with concomitant modulation in the expression of EMT markers.

In the same assay, we tested other clones displaying invasiveness in vitro and tumorigenic and metastatic phenotype in vivo [16].