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The larval metamorphosis model developed here from experimental data demonstrates that reducing water contamination can have positive effects on coral recruitment.
A major advantage of this metamorphosis model is its total dependence on thyroid hormone (T3).
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But Signac's brush strokes create a staccato rhythm that metamorphoses the model.
To further investigate the effect of T4 concentration on induced metamorphosis, we modeled mRNA abundance estimates from the 5 and 50 nM T4 treatments using quadratic and linear regression.
We also investigated whether such As-induced alterations in hormone signaling would lead to pathophysiologic consequences, using amphibian tail metamorphosis as a model system.
Using Xenopus laevis metamorphosis as a model, we and others have shown that the adult intestinal stem cells develop de novo and are distinct molecularly from the larval cells.
This makes amphibian metamorphosis a superior model to study the developmental mechanisms in vivo when compared to mammalian postembryonic development, where maternal influences complicate the studies on the embryos/neonates.
Intestinal metamorphosis is an excellent model to study the development of adult organ-specific stem cells.
Xenopus laevis metamorphosis is an ideal model for studying MMP and TIMP expression levels because all tissues are remodeled under the control of one molecule, thyroid hormone.
In larvaceans, the transparency and absence of a drastic metamorphosis provides a complementary model system for the study of heart development.
The completed analysis resulted in a fully parameterised model of larval metamorphosis success incorporating both the Cu and temperature responses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com