Sentence examples for metabolized to a from inspiring English sources

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Moreover, HPLC/MS metabolic profiling in HepG2 cells showed that flavonoid sulfates 1 3 were metabolized to a limited extent compared to the nonsulfated compounds.

Isoflurane is metabolized to a reactive metabolite that can cause hepatotoxicity, an issue for researchers who are exposed to the anaesthetic on a daily bases.

Our earlier results have shown that a glutathione conjugate of cisplatin is metabolized to a nephrotoxicant via gamma-glutamyl transpeptidase (GGT) and a cysteine S-conjugate beta-lyase.

Obviously, many things ultimately are metabolized to a compound that is sugar [like bread], so it is impossible, of course, to eliminate all sugar from your diet if you take it down to whatever it is metabolized to.

According to recent findings that diversiform isoflavones with common stem nuclei may be intestinally metabolized to Equal for acting on pharmacological targets [13], we predicted that all the seven flavonoid glycosides with common stem nuclei in the EF could be finally intestinally metabolized to a uniform molecule detected in serum.

Incubation of verapamil with heart microsomes led to the formation of nine CYP450-dependent metabolites: a major finding was the observation that stereoselectivity was reversed compared to human liver microsomes, in which the R-enantiomer is metabolized to a greater extent.

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Rivastigmine, has an advantage over other cholinesterase inhibitors as it is metabolized to an inactive metabolite at the site of action, bypassing hepatic metabolic pathways and as a result has unaltered bioavailability in subjects with renal or hepatic impairment.

It will be important to learn if 8CPT-Ade is further metabolized to an active compound.

Lumefantrine is metabolized to an active metabolite, desbutyl-lumefantrine.

Leflunomide (Arava) is a novel isoxazol prodrug that is quickly metabolized to an active metabolite.

However, ticagrelor is also metabolized to an equipotent, active metabolite (AR-C124910XX) by CYP3A4 enzymes.

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