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Zolpidem is metabolized through a variety of CYP450 isozymes, including CYP3A, 2C9, 1A2, 2D6, and 2C19.
Arginine stimulates hormonal release and can be metabolized through a family of NO synthase enzymes to nitrogenous compounds like NO.
In the theca, under the influence of LH, cholesterol is converted to pregnenolone and metabolized through a series of substrates ending in androgen production.
Once ingested, inorganic As (InAs) is metabolized through a series of reduction and oxidative methylation reactions to form monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) (Kitchin 2001).
This point supports the idea that 4-methyl β-ketoadipate enollactone is not further metabolized through a classical β-ketoadipate pathway.
Similar(55)
Forty-six proteidentifiedfied using 1-deoxy-GlcNAlk were also present in the GlcNAlk treated samples, suggesting that these proteins are either simultaneously modified by O-GlcNAc glycosylation or that GlcNAlk can also be metabolized through an "off-target" pathway.
The latter has to be readily metabolized through glycolysis, a process that necessitates the participation of numerous enzymes prior to its utilization by the mitochondria.
H2S is metabolized through oxidation, in a process that occurs efficiently in the mitochondria as catalyzed by a series of enzymes to generate persulfide, sulfite, thiosulfate (S2O32–), and sulfate.
As desipramine is primarily metabolized through CYP2D6, poor metabolizers (defined by a dextromethorphan/dextrorphan ratio 0.3 in an 8-h urine collection) were excluded to avoid potential accumulation during the study washout phases.
In our study, 34% of participants were using a medication metabolized through the CYP2D6 pathway, and 59% used a medication metabolized through the CYP3A4/5 pathway.
Succinate is a mitochondrial substrate metabolized through complex II (CII).
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